Home | Chemogenetics Research Lab

Primary area of interest

Primary Areas of Interest

CRISPR-Cas, Genome engineering, Functional Genomics

We focus on developing functionally enhanced CRISPR-systems for their broader and practical application in gene-editing. We employ protein-engineering and chemogenetics for precise cellular gene-editing and investigate their effect on gene-functions for prospective gene-therapy applications.

Synthetic Biology and Anti-infective Drug Development

We are working on designing synthetic biology methods for developing precision anti-infective agents. Our primary targets are multidrug-resistant pathogenic bacteria like MRSA and Mycobacterium tuberculosis.

Anticancer Drug Development

We work on chemical biology methods for developing targeted chemotherapy. We employ small-molecule probes to decipher the role of various DNA-binding proteins or transcription factors in genome stability, repair, plasticity, oncogenesis, and tumor progression.

Open positions

Join the Chemogenetics Research Lab

Graduate students

December 2023

Junior Research Fellow: Interested in working on Chemical Biology and Medicinal Chemistry are invited to apply. We have one vacancy in Chemistry this time. Candidates with M.Sc. in Organic Chemistry and with a fellowship are encouraged to apply through the Bose Institute portal or contact us at bmaji@jcbose.ac.in

Research Assistant

November, 2023

Project Assistant position. The candidates need to have a BS or M.Sc. in Organic Chemistry. To apply, send your CV and a cover letter to bmaji.cu@gmail.com

Postdoctoral Fellow

As soon as possible

Candidates with Ph.D. in any stream of Biology or in Organic Chemistry can approach for writing a Postdoctoral Fellowship (NPDF, DR. D. S. Kothari Postdoctoral Fellowship, CSIR-RA, etc)